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KMID : 0362619890100090575
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Korean Journal of the History of Dentistry
1989 Volume.10 No. 9 p.575 ~ p.583
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EFFECT OF ISOPROTERENOL ON THE RAT SALIVARY GLAND FUNCTION
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Cheong, Dong Kyun/丁東均
Park, No hee/Lee, Sang Shin/朴魯喜/李相信
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Abstract
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To investigate the role of isoproterenol on the function of rat salivary gland, the authors examined the changes of amylase activity, nitrogen content and several electrolytes contents in the salivary gland of rats after isoproterenol injection.
The results were as follow:
1) Enlargement of salivary glands was observed. Salivary glands were differently,!,-affected, - with submaxillary showing the more, and parotid the least after, chronic -isoproterenolbadmini-.stration.
2) Amylase activity of salivary glands was increased maximally at 2hrs after isoproterenol :injection, and then decreased almost to the normal activity at 24hrs after injection. In .animals starved 24hrs before isoproterenol injection, amylase activity of parotid gland was markedly reduced at 2 hrs after single and 5th injection of isoproterenol
3) Ca content of submaxillary gland was decreased maximally at 2 hrs after isoproterenol injeftion, and then returned to the normal value at 24 hrs after the last injection of isoproterenol in the case of chronic administration.
4) Mg and Na contents of submaxillary glands was increased at 24. hrs after the last injection _in chronic administration.
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